The M65 EpiRat™ ELISA is based on the M5 and M6 antibodies, which bind to the biomarker Keratin-18 (K18). K18 is an intermediate filament protein in epithelial ce...
The M65 EpiRat™ ELISA is based on the M5 and M6 antibodies, which bind to the biomarker Keratin-18 (K18). K18 is an intermediate filament protein in epithelial cells.
The concentration of K18 reflects the amount of overall cell death, both apoptosis and necrosis, in K18-positive cells. Levels of K18 are commonly elevated when the liver endures damage, through disease or toxicological effects.
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